Gargles | Pharmacy Notes

Definition of Gargles

Gargles are aqueous concentrated solutions used for treating the pharynx and nasopharynx (posterior part of mouth). Gargles frequently contains antiseptics, antibiotics, and anesthetics agents.

  • Gargles are supplied in concentrate form so must be diluted with water prior to use.
  • Gargles are brought into intimate contact with the mucous membrane of the throat and allowed to remain in contact with it for few seconds before they are thrown out of the mouth.
  • Phenol or thymol ( in low concentrations) is used as an antibacterial agent in gargles. Also Phenol/thymol  exert a mild anaesthetic effect.
  • KCIO3 (potassium chlorate )is included in gargle preparation for its weak astringent effect, and stimulation of the flow of saliva, which released drugs.

Example of Gargles

Phenol gargle & Potassium chlorate (KCIO3) gargles

Potassium chlorate 30 gm
Patent Blue V 0.009 gm
liquefied phenol 15 ml
Purified water q.s.1000 mL
Phenol gargle & Potassium chlorate (KCIO3) gargles

Use of Gargles

Gargles are concentrated, clear solution used in the posterior region of mouth to prevent the throat infection

  1. As Antiseptic/antibacterial throat infection
  2. Astringent
  3. Relieve soreness in mild throat infection.

Container

  • White fluted glass bottle with plastic screw cap.

Labelling:

1. “For external use only”

2. “Diluted with warm water before use”

3. “Not to be swallowed in large amount”

Storage:

Well closed air tight glass container having plastic screw cap.


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