There are total 150 MCQ included in the Junior Pharmacist (GPSSB) question paper. Here our team has included only MCQ Question of Pharmacy subject/Domain. To get complete Question paper with GK, Language Grammar (English & Gujarati) with pharmacy subject, Please download paper below.
Preview of the Question paper
Q.1) Water attack test is used to identify the alkalinity in
(A) Type-I glass
(B) Type-II glass
(C) Type-III glass
[D] Plastic
Q.2) Starch may be included in tablet formulations as a_____
(A) opacifying agent
(B) disintegrant
[c] Diluent
[d] both b & C
(E) Not Attempted
Q.3) Carbomers may be included in a topical product as____
(A) Preservatives
(B) Sweeteners
(C) Wetting agents
(D) Thickening agents
(E) Not Attempted
Q.4) Which indicator is used in Volhard’s method?
(A) Ferrous ammonium sulphate
(B) Crystal Violet
(C) Methyl Orange
(D) Eosin
(E) None of these
Q.5) The biological half-life of many drugs is often prolonged in newborn infants because of____
(A) a higher degree of protein binding
(B) a lower degree of protein binding
(C) complete absorption of drugs
(D) incompletely developed enzyme systems
(E) Not Attempted
Q.6) Chemoreceptor trigger zone is an area of the _____and plays role in stimulating
(A) Cerebrum, Emesis
(B) Cerebrum, Respiration
(C) Medulla Oblongata, Emesis
(D) Medulla Oblongata, Respiration
(E) Not Attempted
Q.7) Which Vitamin has pteridine ring in its structure?
(A) Folic acid
(B) Pantothenic acid
(D) Riboflavin
(C) Biotin
(E) Not Attempted
Q.8) Cotton fibers consist of the of Gossypium herbaceum seeds)
(A) Trichomes
(C) Pericyclic fibers
(B) Phloem fibers
(D) Regenerated fibers
Q.9) Quinine shows coloured fluorescence with sulphuric acid)
(A) Blue
(B) Red
(C) Green
(D) Pink
(E) Not Attempted
Q.10) Which of the following is a sign or symptom of left sided heart failure?
(A) Peripheral edema
(B) Bilateral rales
(C) Jugular venous distension
(D) Hepatomegaly
(E) Not Attempted
Q.11) Glomerular filtrate is equal to :
(A) Plasma
(B) Blood – (RBCs+ WBCs)
(C) Blood – (Blood Cells + Plasma Proteins)
(D) Serum + Plasma Proteins
(E) Not Attempted
Q.12) Which of the following is a rich source of Vitamin A only?
(A) Shark Liver Oil
(B) Cod Liver Oil
(C) Amla
(E) Not Attempted
(D) Yeast
[S12] Shark Liver oil is rich source of Vitamin A) Cod liver Oil contains both Vit A 7 Vit D, while Shark Liver oil contains only Vit A)
Shark Liver oil:- Biological source→ Hypoprion brevirostris & Galeorhinus zyopterus) As per IP→ 1 g Shark Liver oil contain not less than 6000 IU→ use as Antixerophalmic)
Cod Liver oil→ Biological source→ Gadus morrhua (Gadidae) → Contain both Vit A & Vit D)
Q.13) Which amino acid has hydroxyl group in its side chain?
(A) Serine
(B) Valine
(C) Leucine
(D) Glycine
(E) Not Attempted
Q.14) Mefenamic acid is belonging to which chemical class of non-steroidal anti-inflammatory agent?
[a] Salicylates
(B) Pyrazolidinediones
(C) Anthranilic acid
(D) Heteroaryl acid
(E) Not Attempted
Q.15) Hypodemic needle sizes are expressed by guage numbers) The guage number refers to the
(A) bevel size
(B) external diameter of the cannula
(C) internal diameter of the cannula
(D) length of the needle
(E) Not Attempted
Q.16) Magnesium stearate is used as
(A) Antioxidant
(B) Antiadherent
(C) Disintegrant
(E) Not Attempted
(D) Binder
Q.17) Co-trimoxazole is the combination of
(A) Suplhamethiazole and Trimethoprim
(B) Sulphadiazine and Trimethoprim
(C) Sulphamethoxazole and Triamterene
(D) Sulphamethoxazole and Trimethoprim
(E) Not Attempted
Q.18) Which condition increases the rate of drug dissolution for tablet?
(A) Increase in the particle size of the drug
(B) Decrease in the particle size of the drug
(C) Use of ionized or salt form of the drug
(D) Use of free acid or free base of the drug
(E) Both B & C
Q.19) Standards for disinfectant fluids come under
(A) Schedule O
(B) Schedule R
(C) Schedule S
(E) Not Attempted
(D) Schedule E
Q.20) Carpometacarpal joint of the thumb is an example of:
(A) Saddle Joint
(B) Hinge Joint
(C) Pivot Joint
(D) Ball and Socket Joint
(E) Not Attempted
Q.21) Which of the following substrate inhibits bacterial folic acid synthesis?
(A) Invermectin
(B) Amphotericin
(C) Artesunate
(D) Dapsone
(E) Not Attempted
Q.22) Drug that prevent microtubule polymerization and assembly of microtubule leading to of mitotic spindle is
(A) Procarbazine
(B) Vincristine
(C) Paclitaxel
(D) Dactinomycin
(E) Not Attempted
Q.23) Which inorganic salt is used as an expectorant ?
(A) Magnesium Chloride
(B) Zinc Chloride
(C) Sodium Bicarbonate
(D) Ammonium Chloride
(E) Not Attempted
Q.24) Which narcotic analgesic is considered to be 50 times more potent than morphine?
(a) Fentanyl Citrate
(B) Diphenoxylate hydrochloride
(C) Pethidine
(D) Codeine
(E) Not Attempted
Q.25) Chloroquine belongs to which anti-malarial class? 19
(A) 4-amino quinolines
(B) 9-amino quinolines
(C) 8-amino quinolines
(D) Biguanides
(E) Not Attempted
Q.26) For medicinal purpose, the cold drawn oil of castor seeds is steamed at 80°C to destroy the toxic substance called
(A) Sinigrin
(B) Piperine
(C) Albumin
(D) Ricin
(E) Not Attempted
Q.27) Tidal volume is equal to :
(A) (Total lung capacity) – (Vital capacity)
(B) (Functional residual capacity) – (Expiratory reserve volume)
(C) (Inspiratory capacity) – (Inspiratory reserve volume)
(D) (Residual volume)+(Expiratory reserve volume)
(E) Not Attempted
Q.28) Which of the following statement is true for the rate of creaming of pharmaceutical emulsions?
(A) The rate of creaming is increased as the diameter of the internal phase is increased
(B) The rate of creaming is increased as the viscosity of the continuous phase is increased
(C) The rate of creaming is not affected by the concentration and type of surfactant used
(D) The rate of creaming is decreased by centrifugation
(E) Not Attempted
Q.29) Which of the following has good polishing effect on teeth?
(A) Strontium Chloride
(B) Stannous Fluoride
(C) Zinc Chloride
(D) Magnesium Chloride
(E) Not Attempted
Q.30) Identify aromatase inhibitor
(A) Anastrozole
(B) Finasteride
(C) Clomiphene
(D) Tamoxifen
(E) Not Attempted
Q.31) The term ‘chiral’ is related to drug’s
(A) chelating ability
(B) stability
(C) stereoisomerism
(E) Not Attempted
(D) solubility
Q.32) Which of the following test is not official in Indian Pharmacopoeia 2007 ?
(A) Hardness
(B) Friability
(C) Disintegration
(D) Content Uniformity test
(E) Not Attempted
Q.33) For a solution to be isotonic with blood, it should have the same
(A) salt content
(B) pKa
(C) fluid pressure
(D) osmotic pressure
(E) Not Attempted
Q.34) The germinal epithelium of ovary is
(A) Simple cuboidal epithelium
(B) Simple columnar epithelium
(C) Stratified cuboidal epithelium
(D) Stratified columnar epithelium
(E) Not Attempted
Q.35) Saffron is generally adulterated with dried flowers of carthmus tinctorius’) Identify type of adulteration practice
(A) Replacement with exhausted drugs
(B) Substitution with superficially similar but inferior drugs
(C) Substitution by artificially manufactured substances)
(D) Substitution by sub-standard commercial varieties
(E) Not Attempted
Q.36) Vitamin D3 is also known as__
(A) Cholecalciferol
(B) Ergosterol
(C) Ergocalciferol
(D) 7-deoxy cholesterol
(E) Not Attempted
Q.37) B-Cells of Pancreatic islets secret
(A) Pancreatic polypeptide
(B) Somatostatin
(C) Glucagon
(D) Insulin
(E) Not Attempted
Q.38) Drugs with which of the following half-lives are the best candidates for oral sustained release dosage formulations?
(A) 10-12 hours
(B) 1-2 hours
(C) 4-8 hours
(D) 12-16 hours
(E) Not Attempted
Q.39) Boric acid is dissolved in ____mixture before titrating it with NaOH?
(A) Glycerol-water
(B) Acetone- water
(C) Nitrobenzene – alcohol
(D) Xylene-alcohol
(E) Not Attempted
Q.40) _____ acts by increasing osmotic load of intestine by absorbing large quantity of water)
(A) Bulk Purgative
(B) Lubricants
(C) Saline Cathartics
(D) Stimulants
(E) both A & C
Q.41) pH is equal to pKa at
(A) pH 14
(B) pH 7
(C) the neutralization point
(D) half neutralization point
Q.42) Choose the drug used to treat tapeworm infections:
(A) Niclosamide
(B) Chloroquine
(C) Metronidazole
(D) Ciprofloxacin
(E) Not Attempted
Q.43) Which of the following drug can be used for synthesis of steroidal drugs?
(A) Shankhapushpi
(B) Dioscorea
(C) Picorrhiza
(D) Tobacco
(E) Not Attempted
Q.44) Deficiency of which Vitamin cause lowering of Prothrombin level?
(A) Vitamin D
(B) Vitamin A
(C) Vitamin K
(D) Vitamin C
(E) Not Attempted
Q.45) Tranexamic acid is:
(A) Anti-fibrinolytic agent
(B) Fibrinolytic agent
(C) Anticoagulant
(D) Anti-platelet agent
(E) Not Attempted
Q.46) Blood bank comes under
(A) Schedule B
(B) Schedule D
(C) Schedule F
(D) Schedule G
(E) Not Attempted
Q.47) The “F” value for a drug product is compared to its
(A) absolute bioavailability
(B) dosing rate
(C) clearance rate
(D) elimination rate
(E) Not Attempted
Q.48) Choose the correct symptoms for third degree burns)
(A) Erythema, Swelling, tenderness without dead epithelium
(B) Redness and pain only
(C) Skin become dry, leathery and dead
(D) Blisters and pain
(E) Not Attempted
Q.49) Which of the following purgative drug belongs to Liliaceae family?
(A) Senna
(B) Aloe
(C) Rhubarb
(D) Castor oil
(E) Not Attempted
Q.50) In which of the following dosage forms surface active agents are used in their formulations?
(A) Bulk powder
(B) Ointment
(C) Creams
(D) Dusting powder
Q.51) Which of the following is an example of indiffusible powder?
(A) Chalk BP
(B) Light Kaolin BP
(C) Light Magnesium Carbonate BP
(D) Sodium Bicarbonate BP
(E) Not Attempted
Q.52) The number of deaths in one thousand population in a year in a particular area is defined as:
(A) Morbidity rate
(B) Disability rate
(C) Crude mortality rate
(D) Utilization rate
(E) Not Attempted
Q.53) Which of the following intravenous anaesthetic agent is analogue of phencyclidine and produce dissociative anaesthesia?
(A) Propofol
(B) Thiopental
(C) Etomidate
(D) Ketamine
(E) Not Attempted
Q.54) Which medicinal plant is also used as a source of naturally occurring sweetening agent?
(A) Glycyrrhiza
(B) Peppermint
(C) Acacia
(D) Digitalis
Q.55) The first edition of Indian Pharmacopoeia was published in the year
(A) 1948
(B) 1950
(C) 1955
(D) 1960
(E) Not Attempted
Q.56) Which of the following pairs of chemotherapeutic agents is most commonly used as maintenance in the treatment of Acute Lymphoblastic Leukemia (ALL)?
(A) Fludarabine, Cyclophosphamide
(B) Mercaptopurine, Methotrexate
(C) Vincristine, Imatinib
(D) Daurorubicin, Gemcitabine
(E) Not Attempted
Q.57) The dissolution rate of drug from tablet may be increased by
(A) Increasing the compression pressure during tabletting)
(B) Increasing the concentration of lubricant
(C) Increasing the concentration of disintegrant
(D) Film-coating the tablet with ethylcellulose
(E) Not Attempted
Q.58) is selective 5-HT3 antagonist
(A) Clozapine
(B) Ondansetron
(C) Ketanserin
(D) Risperidone
(E) Not Attempted
Q.59) Identify a drug which forms more potent glucuronide conjugate metabolite as compared to the parent drug
(A) Morphine
(B) Aspirin
(C) Chloramphenicol
(D) Levodopa
(E) Not Attempted
Q.60) Which of the following drug is a salt of a weak acid and strong base)
(A) Chlorpromazine hydrochloride
(B) Sodium salicylate
(C) Acetyl salicylic acid
(D) Chlorpheniramine maleate
(E) Not Attempted
Q.61) Which radioisotope is used to diagnose pernicious anemia ?
(A) Carbon (14C)
(B) Cobalt (57Co)
(C) Gold (198Au)
(D) Iodine (131I)
(E) Not Attempted
Q.62) Which antidote is used in copper poisoning?
(A) D-Penicillamine
(B) Kaolin
(C) Sodium Phosphate
(D) Magnesium Sulphate
(E) Not Attempted
Q.63) The colligative properties of a solution are related to the
(A) total number of solute particles
(B) pKa
(C) number of unionized molecules
(D) Number of Ions
(E) Not Attempted
Q.64) Identify, H2-receptor blocker from the drugs given below?
(A) Ranitidine
(B) Cyproheptadine
(C) Omeprazole
(D) Cetirizine
Q.65) The ‘0’ size capsules can fill the volume of
(A) 0)75 ml
(B) 2)95 ml
(C) 1)36 ml
(D) 0)15 ml
(E) None
Q.66) Which of the following drug follows zero order kinetics for metabolism?
(A) Phenytoin
(B) Cetirizine
(C) Loratidine
(D) Valproic acid
(E) Not Attempted
Q.67) Choose the correct incubation period for diphtheria)
(A) 1-2 days
(B) 7-14 days
(C) 2-4 weeks
(D) 2-4 days
(E) Not Attempted
Q.68) How many nitrogen atoms are present in pyrimidine ring?
(A) 1
(B) 4
(C) 3
(D) 2
(E) Not Attempted
[S68]
Q.69) The absorption rate of a drug is most rapid when drug is formulated as
(A) Soft gelatin capsule
(B) Hard gelatin capsule
(C) Compressed tablet
(D) Solution
(E) Not Attempted
Q.70) Which heteropolysaccharide is made up of repeating unit of D-glucuronic acid and N-acetyl D-glucosamine?
(A) Heparin
(B) Chondroitin
(C) Chitin
(D) Hyaluronic acid
(E) Not Attempted
Q.71) Which of the following is an active constituent of Ipecacuanha root?
(A) Cephaeline
(B) Aconitine
(C) Colchicine
(D) Strychnine
(E) Not Attempted
Q.72) Dry cough is a common adverse effect of
(A) Angiotensin receptor blockers
(B) Angiotensin converting enzyme inhibitors
(C) Loop diuretics
(D) Thiazide diuretics
Q.73) Which local anaesthetics is the ester of para amino benzoic acid?
(A) Lignocaine
(B) Bupivacaine
(C) Procaine
(D) Hexylcaine
(E) Not Attempted
Q.74) Which heterocyclic ring is present in metronidazole ?
(A) Pyrrole
(B) Pyrazole
(C) Imidazole
(D) Indole
(E) Not Attempted
[S74]
Q.70) ____is the example of Phosphoprotein)
(A) Hyaluronic acid
(B) Casein
(C) Hemoglobin
(E) Not Attempted
(D) Cholesterol
GPSSB Junior Pharmacist Solved Question Paper 2022 pdf: Download↓
Junior Pharmacist Paper 2022-GPSSB GJ
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